SFB / Transregio 23
"Vascular Differentiation and Remodeling"

Mannheim - Heidelberg - Frankfurt

PD Dr. Tobias Bäuerle Molecular Imaging Group Medical Physics in Radiology (E020) Im Neuenheimer Feld 280 D-69120 Heidelberg Phone: 0049 (0)6221 42 2569 Lab Homepage
	t.baeuerle(at)dkfz.de
Z1: Non-invasive assessment of tissue micro-morphology, vessel function and cell migration in vivo with contrast-enhanced MRI, VCT and sonography
Non-invasive imaging of tumor growth, angiogenesis and vessel function has become highly relevant in angiogenesis research. We have employed magnetic resonance imaging (MRI), flat panel volumetric computed tomography (VCT) and ultrasound (US) for the imaging of vascularization and perfusion in small animals. We successfully developed novel contrast-enhanced and molecular imaging techniques to monitor tumor vascularization, blood volume and vessel permeability. We now aim to further optimize established methods, extend our cell tracking modalities and apply our recently developed tri-modality scanner combining micro CT, single photon emission computed tomography and optical imaging in a single device.